operate

verb:to function or work in a particular way
- The machine is designed to operate quietly and efficiently.
verb:to perform a surgical procedure
- The surgeon will operate on the patient's knee tomorrow morning.
verb:to control or manage the functioning of a machine, device, or system
- He knows how to operate most of the machines in the factory.
verb:to be in effect or to function
- The medicine began to operate quickly, relieving his pain.